1. Unexplained Weight Loss

Unexpected weight loss is one of the most common signs of pancreatic cancer. Even if your diet and activity levels remain the same, the disease can interfere with digestion and nutrient absorption. Tumors may block enzymes the pancreas needs to break down food, leading to malnutrition.

Case example: John, age 52, lost 15 pounds in two months without dieting. His doctor initially suspected diabetes but further testing revealed pancreatic cancer.

If you notice significant weight loss—typically more than 5% of your body weight in 6–12 months—without explanation, schedule an evaluation with your healthcare provider.

2. Persistent Abdominal or Back Pain

Pain that lingers in the upper abdomen and radiates to the back can indicate a tumor pressing against nearby nerves or organs. Many people describe it as a dull ache that worsens after eating or when lying down.

This symptom is easily overlooked as indigestion, gallbladder problems, or muscle strain. However, if the pain is persistent, gets worse over time, or interferes with sleep, it deserves medical attention.

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